ScienceDaily: Biotechnology News |
- Deadly parasite juggles the number of its chromosomes
- Cell cultures from a machine
- Different paths to drug resistance in Leishmania: Evolution by changes in gene, region and chromosome number, not by mutation in genes
- Vaccine for cattle offers hope to poorest farmers
- How major signaling pathways are wired to our genome gives new insight into disease processes
| Deadly parasite juggles the number of its chromosomes Posted: 28 Oct 2011 08:36 AM PDT Scientists have found a deadly parasite with some of its chromosomes in duplicate, others in triplicate, while still others are present four or even five times. Moreover, the copy number varies between individuals. Such a bizarre occurrence has never before been found in nature, in any organism. As a rule, chromosomes should come in couples. Scientists made the striking discovery while deciphering the genetic code of a series of Leishmania parasites.  |
| Posted: 28 Oct 2011 07:32 AM PDT Cell cultures form the basis of day-to-day research work in applications that range from the development of drugs and vaccines to the decoding of functions of individual genes. Up until now, cell cultures have been sown, tended, observed and transferred to vessels -- all by hand. A new device automates these worksteps completely.  |
| Posted: 27 Oct 2011 02:35 PM PDT Two remarkable discoveries have been revealed by researchers into genome analysis of Leishmania parasites. These results uncovered a surprising level of variation at the genome structure level.  |
| Vaccine for cattle offers hope to poorest farmers Posted: 27 Oct 2011 02:35 PM PDT A new approach to vaccinating cattle could help farmers worldwide, research suggests. Scientists have developed a technique using a harmless parasite, which lives in cows but has no effect on their health, to carry medicines into the animals' bloodstream.  |
| How major signaling pathways are wired to our genome gives new insight into disease processes Posted: 27 Oct 2011 09:51 AM PDT Scientists have determined that master transcription factors determine the genes regulated by key signaling pathways. In this way, signaling pathways are targeted to genes that are most relevant to each cell type and tailor gene expression to control cell state, growth, differentiation, and death. By manipulating signaling pathways, scientists may find new therapies for cancer and other diseases or ways to push cells into more specialized states, such as neurons to treat nerve damage or insulin-producing beta cells for diabetes.  |
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