ScienceDaily: Biotechnology News |
- New information on the waste-disposal units of living cells
- Simpler times: Did an earlier genetic molecule predate DNA and RNA?
- Evolution of complexity recreated using 'molecular time travel'
- Cbx proteins and the fate of embryonic stem cells
| New information on the waste-disposal units of living cells Posted: 11 Jan 2012 12:40 PM PST Researchers have provided the most detailed look ever at the "regulatory particle" used by the proteasome - one of the most critical protein machines in living cells - to identify and degrade proteins marked for destruction. This new information holds implications for a broad range of vital biochemical processes, including transcription, DNA repair and the immune defense system.  |
| Simpler times: Did an earlier genetic molecule predate DNA and RNA? Posted: 09 Jan 2012 07:30 AM PST Scientists have described the Darwinian evolution of functional TNA molecules from a large pool of random sequences. This is the first case where such methods have been applied to molecules other than DNA and RNA, or very close structural analogues thereof. One of the researchers said "the most important finding to come from this work is that TNA can fold into complex shapes that can bind to a desired target with high affinity and specificity."  |
| Evolution of complexity recreated using 'molecular time travel' Posted: 08 Jan 2012 11:35 AM PST Scientists have now demonstrated how just a few small, high-probability mutations increased the complexity of a molecular machine more than 800 million years ago. By biochemically resurrecting ancient genes and testing their functions in modern organisms, the researchers showed that a new component was incorporated into the machine due to selective losses of function rather than the sudden appearance of new capabilities.  |
| Cbx proteins and the fate of embryonic stem cells Posted: 05 Jan 2012 10:15 AM PST Researchers have published an innovative study on the role of Cbx proteins in the genetic regulation of embryonic stem cells. The study revealed that changes in the expression of specific Polycomb group proteins modulate the function of the Polycomb complex during both embryonic stem cell differentiation and tumorigenesis.  |
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