Wednesday, July 27, 2011

ScienceDaily: Biotechnology News

ScienceDaily: Biotechnology News


How the modular structure of proteins permits evolution to move forward

Posted: 26 Jul 2011 04:00 PM PDT

A new study compares the development of the egg laying organ in two species of nematodes; with its results providing support for the theory of developmental systems drift. This theory maintains that, over the course of evolution, analogous organs of different species can retain the same shape and function while the regulative mechanisms underlying their development can change considerably.

More powerful 'lab-on-a-chip' made for genetic analysis

Posted: 26 Jul 2011 01:35 PM PDT

Researchers have invented a silicone chip that could make genetic analysis far more sensitive, rapid, and cost-effective by allowing individual cells to fall into place like balls in a pinball machine. The device -- about the size of a nine-volt battery -- allows scientists to simultaneously analyze 300 cells individually by routing fluid carrying cells through microscopic tubes and valves. By facilitating such "single-cell analysis," the device could accelerate genetic research and hasten the use of far more detailed tests for diagnosing cancer.

3-D atomic structure of popular drug target determined

Posted: 26 Jul 2011 06:29 AM PDT

Scientists have revealed the complete three-dimensional atomic structure of an activated GPCR (beta-2AR) in a complex with its G protein. G protein-coupled receptors (GPCRs) are popular drug targets, accounting for about one-third of approved drugs and many hundreds of drugs currently in development.

Epigenetic 'memory' key to nature versus nurture

Posted: 24 Jul 2011 10:55 AM PDT

Researchers have made a discovery that explains how an organism can create a biological memory of some variable condition, such as quality of nutrition or temperature. The discovery explains the mechanism of this memory -- a sort of biological switch -- and how it can also be inherited by offspring.

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