ScienceDaily: Biotechnology News |
- New approach to link genome-wide association signals to biological function
- Telomeres: Two genes linked to why they stretch in cancer cells
- MicroRNAs in the songbird brain respond to new songs
- Genetic alterations in pig tissue may allow for human transplantation
- Using DNA in fight against illegal logging
- Many a mickle makes a muckle: How changes in animals’ size and shape arise
- Conservation of genetic structure in lake salmonids affected by hydropower regulation, release of fish and hybrids
| New approach to link genome-wide association signals to biological function Posted: 30 Jun 2011 02:17 PM PDT Researchers have identified a new strategy to improve the outcome of genome-wide association (GWA) studies. This will lead to a better understanding of the function of affected genes and the biological pathways involved, potentially translating these findings into clinical benefits. It is estimated that this approach, which finds the open chromatin regions in human cells, could be used in one in four GWA studies.  |
| Telomeres: Two genes linked to why they stretch in cancer cells Posted: 30 Jun 2011 11:28 AM PDT Scientists have provided more clues to one of the least understood phenomena in some cancers: why the "ends caps" of cellular DNA, called telomeres, lengthen instead of shorten.  |
| MicroRNAs in the songbird brain respond to new songs Posted: 30 Jun 2011 09:20 AM PDT Whenever it hears an unfamiliar song from a male of the same species, a zebra finch stops chirping, hopping and grooming. Once it becomes familiar with the song, it goes back to its busy routine. Researchers have now found that levels of microRNAs -- short lengths of ribonucleic acid -- go up or down in the songbird brain after it hears a new song. These microRNAs likely represent a new class of regulatory agents that fine-tune the brain's response to social information.  |
| Genetic alterations in pig tissue may allow for human transplantation Posted: 30 Jun 2011 08:28 AM PDT A sizzling genetic discovery may one day allow pig tissue to be transplanted successfully into humans. Scientists have taken a step forward toward filling the shortage of vital organs for human transplantation. Research has shown that altering or overexpressing human programmed death ligand-1 molecule in endothelial cells of pig arteries reduces conditions that cause rejection. This suggests humans could receive altered porcine organs with fewer complications.  |
| Using DNA in fight against illegal logging Posted: 30 Jun 2011 08:26 AM PDT Advances in DNA "fingerprinting" and other genetic techniques are making it harder for illegal loggers to get away with destroying protected rainforests.  |
| Many a mickle makes a muckle: How changes in animals’ size and shape arise Posted: 30 Jun 2011 04:33 AM PDT The natural world contains great diversity in the shape and size of organisms. But how does this variety evolve? Researchers are investigating changes in morphology in fruit flies and have managed to show how a gene enhancer (a piece of DNA that controls the timing and level of a gene's expression) can change its function through stepwise changes in DNA sequence to give rise to differences in animals' appearance.  |
| Posted: 28 Jun 2011 06:48 AM PDT The negative effects of releasing fish and the possible fragmentation of natural fish stocks in connection with hydropower regulations may be fewer than at first feared. New research shows that the genetic structure of established stocks of wild trout and charr is only affected to a small extent by human intervention in the study area.  |
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