Friday, November 04, 2011

ScienceDaily: Biotechnology News

ScienceDaily: Biotechnology News


Fertilized oocytes digest paternal mitochondria

Posted: 03 Nov 2011 11:35 AM PDT

During fertilization, the entire spermatozoon enters the oocyte. However, most of its organelles, including mitochondria, are not transmitted to the offspring. A new study demonstrates for the first time how the spermatozoon organelles are digested by the oocyte shortly after fertilization. These findings could improve cloning and medically-assisted reproductive technology and help to better understand the evolutionary origin of the elimination of paternal mitochondria.

Discovery of new gene could improve efficiency of molecular factories

Posted: 03 Nov 2011 11:34 AM PDT

The discovery of a new gene is helping researchers envision more-efficient molecular factories of the future.

Chromosome centromeres are inherited epigenetically

Posted: 03 Nov 2011 11:32 AM PDT

The histone protein CenH3 is both necessary and sufficient to trigger the formation of centromeres and pass them on from one generation to the next.

Alternate ending: Living on without telomerase

Posted: 03 Nov 2011 09:24 AM PDT

Scientists have discovered an alternative mechanism for the extension of the telomere repeat sequence by DNA repair enzymes.

Pulsating response to stress in bacteria discovered

Posted: 03 Nov 2011 09:06 AM PDT

Turning on the heater is a reasonable response to a cold environment: switch to a toastier state until it warms up outside. Biologists have long thought cells would respond to their environment in a similar way. But now researchers are finding that cells can respond using a pulsating mechanism. The principles behind this process are surprisingly simple and could drive other cellular processes, revealing more about how the cells -- and ultimately life -- work.

Gene therapy shows promise as hemophilia treatment in animal studies

Posted: 03 Nov 2011 05:14 AM PDT

For the first time, researchers have combined gene therapy and stem cell transplantation to successfully reverse the severe, crippling bleeding disorder hemophilia A in large animals, opening the door to the development of new therapies for human patients.

Nicotine primes brain for cocaine use: Molecular basis of gateway sequence of drug use

Posted: 02 Nov 2011 04:04 PM PDT

Cigarettes and alcohol serve as gateway drugs, which people use before progressing to the use of marijuana, cocaine and other illicit substances; this progression is called the "gateway sequence" of drug use. Latest findings provide the first molecular explanation for the gateway sequence. They show that nicotine causes specific changes in the brain that make it more vulnerable to cocaine addiction -- a discovery made by using a novel mouse model.

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