ScienceDaily: Biotechnology News |
- Modeling melanocyte differentiation in zebrafish
- Tree-killing pathogen traced back to California
- Glowing, blinking bacteria reveal how cells synchronize biological clocks
- Biological 'computer' destroys cancer cells: Diagnostic network incorporated into human cells
- Scientists discover secret life of chromatin: DNA/histone combination, a destination for cell signals, also talks to other proteins
- Insect gut microbe with a molecular iron reservoir: Researchers analyze the structure of an iron storage protein
- MIABE standard opens up new opportunities in drug discovery
| Modeling melanocyte differentiation in zebrafish Posted: 01 Sep 2011 02:12 PM PDT Researchers have combined genetic data with mathematical modeling to provide insights into cells and how they differentiate. The findings demonstrate the utility of a systems biology approach and could have implications for understanding and treating diseases, including cancers, caused when cells start to function incorrectly.  |
| Tree-killing pathogen traced back to California Posted: 01 Sep 2011 11:26 AM PDT California has emerged as the top suspect as the source of a pathogen responsible for a global pandemic of cypress canker disease. The genetic detective work by researchers in the U.S. and in Italy spotlights the hazards of planting trees and other vegetation in regions where they are not native.  |
| Glowing, blinking bacteria reveal how cells synchronize biological clocks Posted: 01 Sep 2011 11:21 AM PDT Biologists have long known that organisms from bacteria to humans use the 24 hour cycle of light and darkness to set their biological clocks. But exactly how these clocks are synchronized at the molecular level to perform the interactions within a population of cells that depend on the precise timing of circadian rhythms is less well understood.  |
| Biological 'computer' destroys cancer cells: Diagnostic network incorporated into human cells Posted: 01 Sep 2011 11:20 AM PDT Researchers have successfully incorporated a diagnostic biological "computer" network into human cells. This network recognizes certain cancer cells using logic combinations of five cancer-specific molecular factors, triggering cancer cells destruction.  |
| Posted: 01 Sep 2011 10:46 AM PDT Chromatin -- the intertwined histone proteins and DNA that make up chromosomes -- constantly receives messages that pour in from a cell's intricate signaling networks: Turn that gene on. Stifle that one. But chromatin also talks back, scientists report, issuing orders affecting a protein that has nothing to do with chromatin's central role in gene transcription -- the first step in protein formation.  |
| Posted: 01 Sep 2011 07:54 AM PDT Iron plays an important role in almost every life form. Low iron can lead to deficiency symptoms and reduced growth, whereas too much iron may harm biomolecules like DNA. Researchers in Germany have now elucidated the spatial structure of a bacterial enzyme in Microbacterium arborescens which is able to accumulate several hundred iron ions in its center -- depending on the iron supply situation in its environment: for example in the larval gut of the beet armyworm Spodoptera exigua.  |
| MIABE standard opens up new opportunities in drug discovery Posted: 31 Aug 2011 05:17 AM PDT Life science data providers have agreed on a new standard for describing the effect of a compound on a biological entity. The new standard makes it possible to enhance the interchange of public data on drug discovery success and attrition.  |
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